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NAD+ 500 mg

product on market Capsule Double Wood Supplements Safety: 60/100
60/100

Review before taking

  • Nicotinamide Adenine Dinucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Nicotinamide Adenine Dinucleotide is used to support cellular energy metabolism, though clinical evidence for oral supplementation remains limited. Due to a safety score of 60, potential concerns regarding long-term tolerability should be noted. Users should exercise caution and consult a professional regarding its safety profile.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide Adenine Dinucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of NAD+ exceeds the recommended upper intake limit by over 14 times.

Label

Product Label

Label for NAD+ 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Hypromellose Rice Flour
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement take 2 capsules (1 serving) per day on an empty stomach.

Warnings & Precautions

Warning: Consult your physician before use.

Do not use NAD+ if you are pregnant, nursing, or under 18 years of age.

Do not use NAD+ if you are pregnant, nursing, or under 18 years of age.

Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use NAD+ and operate heavy machinery until you know how it affects you.

Keep out of reach of children.

Do not exceed 2 capsules per day.

Formulation Notes

Product Info: NAD+ (Nicotinamide Adenine Dinucleotide) is an important coenzyme found in all human cells. It plays a role in hundreds of different metabolic processes but declines as we age.

Made with Non-GMO Ingredients Gluten Free

NAD+ 500 mg per serving Nicotinamide Adenine Dinucleotide

Additional Information

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature after opening.

Metadata

Product Details

UPC / SKU8 50033 27282 6
DSLD Entry Date2024-09-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandDouble Wood Supplements
DSLD ID315686
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.