🟡 60/100

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  • Nicotinamide Adenine Dinucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
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Safety Alerts

⚠️ Nicotinamide Adenine Dinucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

This product received a low safety score because its 500mg dose of NAD+ is more than 14 times higher than the recommended maximum daily intake of 35mg.

Label Data

2 Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg

Other Ingredients

Hypromellose Rice Flour

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement take 2 capsules (1 serving) per day on an empty stomach.

⚠️ Warnings & Precautions

Warning: Consult your physician before use.

Do not use NAD+ if you are pregnant, nursing, or under 18 years of age.

Do not use NAD+ if you are pregnant, nursing, or under 18 years of age.

Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use NAD+ and operate heavy machinery until you know how it affects you.

Keep out of reach of children.

Do not exceed 2 capsules per day.

🧪 Formulation Notes

Product Info: NAD+ (Nicotinamide Adenine Dinucleotide) is an important coenzyme found in all human cells. It plays a role in hundreds of different metabolic processes but declines as we age.

Made with Non-GMO Ingredients Gluten Free

NAD+ 500 mg per serving Nicotinamide Adenine Dinucleotide

Additional Information

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature after opening.

Product Details

UPC / SKU 8 50033 27282 6
DSLD Entry Date 2024-09-25
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 315686
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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