🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 30% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
30% Evidence Coverage

Supplement Facts — Evidence Check

Calcium
129 mg (10% DV)
78 mg (6% DV)
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 78mg UL 4000mg
117 mg (5% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 117mg
Potassium
123 mg (3% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 750mg
NEM
250 mg
HerbaZyme Soothing Blend
200 mg
TamaFlex
125 mg
ApresFlex
50 mg
Bovine Cartilage
50 mg

Other Ingredients

Microcrystalline Cellulose Cellulose Magnesium Stearate Hypromellose Glycerin Hydroxypropyl Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (7% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Doctor's Suggested Use: Take 4 tablets daily - 2 with breakfast and 2 with lunch or dinner.

⚠️ Warnings & Precautions

Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.

Keep out of reach of children.

Contains: Shellfish (shrimp, crab), egg

🧪 Formulation Notes

Joint Advantage Gold 5X Turmeric helps promote joint comfort, ease stiffness, and support healthy cartilage 5X represents the unique combination of 5 joint-nurturing ingredients in this formula.

Unconditionally guaranteed for purity and labeled potency.

Due to the nature of these ingredients, color variation may occur.

Glucosamine + Clinically validated NEM Tamaflex & Apresflex

Joint health Mobility Comfort Inflammatory support

GF Gluten free

Additional Information

Almost Out? Call 1-800-888-1415 or visit healthdirections.com Choose Refill & Save, and never run out!

Store bottle with cap tightly closed in a cool, dry place.

Chiropractor developed

Product Details

UPC / SKU 8 10047 39098 5
DSLD Entry Date 2024-07-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 315351
Data Updated 2026-04-11

Research Evidence

311 Research Sources
54 Avg Quality Score
121 Systematic Review
98 Meta Analysis
70 Rct
16 Clinical Trial
2 Other
1 Narrative Review
1 Openfda Safety
A The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis
Meta Analysis Bioscience reports 2021
B Curcumin for depression: a meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2020
B Effect of Aromatic Herbs and Spices Present in the Mediterranean Diet on the Glycemic Profile in Type 2 Diabetes Subjects: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2024
B Complementary and Alternative Medicine Therapies for Psoriasis: A Systematic Review
Meta Analysis JAMA dermatology 2018
B Functional foods modulating inflammation and metabolism in chronic diseases: a systematic review
Systematic Review Critical reviews in food science and nutrition 2022
B Effect of curcumin supplementation on symptoms of anxiety: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2024
B The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis
Meta Analysis Complementary therapies in medicine 2021
B Efficacy of Curcumin-Mediated Antimicrobial Photodynamic Therapy on Candida spp.-A Systematic Review
Systematic Review International journal of molecular sciences 2024
B Effects of curcumin on serum inflammatory biomarkers in patients with knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis BMC complementary medicine and therapies 2025
B Natural Products in Alzheimer's Disease: A Systematic Review of Clinical Trials and Underlying Molecular Mechanisms
Systematic Review International journal of molecular sciences 2025
View all evidence for Curcumin →

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