🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
60 Servings
Amino acid/Protein Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

1 Gram(s)
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 1mg

Other Ingredients

Croscarmellose Sodium Hydroxypropyl Cellulose Stearic Acid Magnesium Stearate Hypromellose Calcium Carbonate Glycerin Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (61% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Halal Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 tablet 1 to 3 times daily on an empty stomach, with final dose at bedtime, or as directed by your physician.

⚠️ Warnings & Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication (especially antidepressants such as SSRIs and MAOIs), or have a medical condition.

May cause drowsiness. Do not use with alcoholic beverages or while operating heavy machinery.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

Tryptophan is an essential amino acid; therefore, it is not synthesized by the body and must be obtained from the diet. Tryptophan is critical for the production of serotonin and melatonin, which help to support a positive mood, healthy sleep patterns, and proper immune system function.

Every lot of NOW L-Tryptophan is tested to be free of peak E and microbial contamination.

Supports relaxation Encourages positive mood Promotes restful sleep

Non-GMO

Triangle K (Kosher)

Vegetarian/Vegan

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or sesame ingredients.

NOW Double Strength L-Tryptophan has twice the L-Tryptophan (1000 mg per tablet) as in our regular strength product (500 mg per capsule).

Crescent H (Halal)

Additional Information

Triangle K (Kosher)

Amino Acids Family owned since 1968.

Crescent H (Halal) GMP Quality Assured

This bottle is made from 100% PCR (post-consumer recycled) resin.

Store in a cool, dry place after opening.

Product Details

UPC / SKU 7 33739 00169 6
DSLD Entry Date 2024-06-20
Product Type Amino acid/Protein
Form Tablet or Pill
Brand NOW
DSLD ID 314285
Data Updated 2026-04-11

Research Evidence

29 Research Sources
48 Avg Quality Score
19 Rct
5 Meta Analysis
3 Systematic Review
2 Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002
View all evidence for Tryptophan →

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