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Niacin 500 mg

product on market Capsule NOW Safety: 60/100
60/100

Review before taking

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol levels and cardiovascular health, though research evidence for these effects varies. Due to a lower safety score, users should be aware of potential concerns such as flushing or liver enzyme changes. Evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin exceeds the recommended daily upper limit by over 14 times.

Label

Product Label

Label for Niacin 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veg. Capsule(s)
Serving Size
100
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Hypromellose Cellulose Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Take 1 capsule daily as needed, with a meal. This high potency capsule should be taken under doctor's supervision.

Warnings & Precautions

Caution: For adults only. Keep out of reach of children.

Do not exceed recommended dose. Do not take on an empty stomach. This product may cause a temporary flush, itching or tingling red rash on the skin. This reaction is normal and harmless. If you experience any prolonged discomfort, discontinue use and consult your physician.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation Notes

Natural color variation may occur in this product. Nutritional Health

Vitamin B-3

Triangle K (Kosher)

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Vegetarian/Vegan

Additional Information

Vitamins Family owned since 1968.

Store in a cool, dry place after opening.

Triangle K (Kosher) GMP Quality Assured

This bottle is made from 100% PCR (post-consumer recycled) resin.

Metadata

Product Details

UPC / SKU7 33739 00481 9
DSLD Entry Date2024-06-20
Product TypeVitamin
FormCapsule
BrandNOW
DSLD ID313877
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.