🟢 87/100

This product is generally safe

  • Manganese: 12mg is 1.1× the Tolerable Upper Intake Level (11mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Manganese: 12mg is 1.1× the Tolerable Upper Intake Level (11mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 200mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 450mg
MSM
250 mg
📊 Market median: 1000.0mg (2 products)
This product: 250mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 215mg
Vitamin C
115 mg (200% DV)
Vitamin C
30 mg (50% DV)
Calcium
40 mg (4% DV)
15 mg (4% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 15mg
30 mg (8% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 30mg
3.5 mg (25% DV)
✅ Within RDA (0.3× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 3.5mg UL 40mg
12 mg (600% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 12mg UL 11mg
Proprietary Blend
148 mg

Other Ingredients

Cellulose Water

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Dosage: Adults or children 12 or more years of age, take two capsules two times a day, or as directed.

⚠️ Warnings & Precautions

Keep out of reach of children.

Consult a physician if pregnant, nursing or allergic to aspirin.

Consult a physician if pregnant, nursing or allergic to aspirin.

🧪 Formulation Notes

Supports the maintenance of healthy joints, tendons, elasticity and cartilage.

EDS: Added enzymes for better absorption & breakdown. AdPT: Adaptogenic herbs for energy production & adaptation.

Gluten free Non GMO No fillers 3x tested

Premium quality

Additional Information

Made in USA

2 Please recycle

Product Details

UPC / SKU 8 98175 00161 4
DSLD Entry Date 2024-03-22
Product Type Other Combinations
Form Capsule
DSLD ID 308990
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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