Joint Ease

product on market Tablet or Pill Nugevity 🟢 Safety: 100/100
Brand: Nugevity
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

3 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

30 mg (150% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
1500 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1500mg
1000 mg
📊 Market median: 1000.0mg (2 products)
This product: 1000mg
ASU Concentrate Blend
320 mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Silica Magnesium Stearate Hydroxypropyl Methylcellulose Polydextrose Titanium Dioxide Medium Chain Triglyceride

Label Claims — Verification

❓ All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Take three (3) tablets daily, preferably with a meal.

⚠️ Warnings & Precautions

Keep out of the reach of children.

Consult your doctor prior to use if pregnant, ill, or taking prescription medications.

Contains shrimp and soy ingredients.

To report an adverse event: 800-820-1710 nugevity.com

🧪 Formulation Notes

This medical-grade formula is manufactured at an FDA registered laboratory, using technologies jointly developed with NASA under a Space Act Agreement. To learn more about our unmatched quality standards, visit nasa.nugevity.com

BioRelease tablets

GF Wheat & gluten free Safe No banned substances

Real Food-based ingredients

Green Sustainable & BPA free

Additional Information

Space Act Technology

Store product in a dry place at controlled room temperature (77 degrees F). Do not expose to heat or moisture.

Product Details

UPC / SKU 8 52015 00321 3
DSLD Entry Date 2024-06-20
Product Type Other Combinations
Form Tablet or Pill
Brand Nugevity
DSLD ID 308118
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
PubMed DOI
View all evidence for Niacin →

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