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Osteo Bi-Flex Triple Strength + Vitamin D

product on market Tablet or Pill Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine hydrochloride and vitamin D are used to support joint health and bone density, though research on glucosamine's efficacy shows mixed results. Evidence for these ingredients is generally moderate to limited depending on the specific joint condition. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex Triple Strength + Vitamin D
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
40
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrate
2 Gram(s) (1% DV)
50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
Sodium
20 mg (1% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Cellulose Crospovidone Cellulose Coating Hydroxypropyl Methylcellulose Magnesium Silicate Medium Chain Triglyceride Polydextrose Silica Titanium Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 Per day Directions for adults use: take two (2) tablets per day preferably with food. As a reminder, discuss the supplements and medications you take with your health care providers.

Warnings & Precautions

Keep out of reach of children.

Tamper resistant: do not use if seal under cap is broken or missing. Discontinue use and consult your doctor if any adverse reactions occur.

Caution: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Not intended for use by persons under the age of 18.

Contains shellfish (crab, crayfish, lobster, shrimp) ingredients.

Formulation Notes

Osteo Bi-Flex is America's #1 Joint Health brand and supports joint comfort, so you can enjoy a range of motion for your day's activities. Based on Kelsen data for the 52 weeks ending June 30, 2018.

Osteo Bi-Flex Triple Strength with Vitamin D contains glucosamine which helps strengthen joints while helping to maintain joint cartilage essential for comfortable joint movement. Vitamin D is also included to help maintain healthy bones in adults.

Osteo Bi-Flex is manufactured under the highest standards for product quality, purity and potency.

Joint health Shows improved joint comfort within 7 days! Based on two human studies with 5-LOXIN ADVANCED where subjects rated their joint health over time, subjects rated their joint health over time, subjects' joint health improved within 7 days, and continued to improve throughout the duration of the studies.

Triple strength + vitamin D Refers to level of key ingredients in each individual tablet. Glucosamine chondroitin with joint shield

This product contains 50 mcg of vitamin D, which is equivalent to 2,000 IU.

Free of gluten

Made in the USA with select ingredients from around the world.

Additional Information

Range of motion During the day, you move your joints in so many different ways, getting up, sitting down, bending and flexing.

To learn more about Osteo Bi-Flex visit www.osteobiflex.com or call us toll free 1-888-VITAHELP (848-2435).

Store at room temperature and avoid excessive heat.

Individuals results may vary.

#1 Pharmacist Recommended Brand Based on the results of the Pharmacy Times Survey among pharmacists who recommend a "bone/joint strengthener" dietary supplement, 2018-2019.

Metadata

Product Details

UPC / SKU0 30768 19607 3
DSLD Entry Date2024-03-22
Product TypeOther Combinations
FormTablet or Pill
BrandOsteo Bi-Flex
DSLD ID307941
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.