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Osteo Bi-Flex Joint & Muscle

product on market Other (e.g. tea bag) Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine HCl is supported by moderate evidence for reducing joint discomfort and improving mobility. The proprietary Joint Shield blend contains additional components aimed at joint support, though specific evidence for the blend's combined efficacy is limited. These ingredients are generally recognized as safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex Joint & Muscle
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
37
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 {Calories}
Total Carbohydrates
2 Gram(s) (1% DV)
Sodium
20 mg (1% DV)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Joint Shield(TM) Proprietary Blend
375 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)

Other Ingredients

Crospovidone Cellulose Contains <2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Qualified Health
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS FOR ADULT USE: TAKE TWO (2) CAPLETS PER DAY WITH FOOD.

Warnings & Precautions

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

CAUTION: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

GLUCOSAMINE CHONDROITIN

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Free of Gluten

So Osteo Bi-Flex(R) Joint & Muscle is specially formulated with Glucosamine, which is naturally produced in our body as a building block of joint cartilage, plus Co Q-10 for your muscles.*

Additional Information

Co Q-10 is an important bioenergetic compound naturally present in the muscle where its normal role is to support energy production from food.*

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

#This statement is based on two human studies of 5-LOXIN(R) Advanced using subjective measures in which participants rate their joint health. In these studies, after 7 days, improvement continued to be seen, including in biomarker analysis.

^Based on results of a GfK Healthcare 2011 survey among physicians who recommend a brand of Glucosamine and Chondroitin or Glucosamine supplements; and the results of a Pharmacy Times Survey among pharmacists who recommend a “bone/joint strengthener” dietary supplement, 2006 -2012.

THE #1 DOCTOR & PHARMACIST RECOMMENDED BRAND!^

HELPS TO: >Support Joint Health* >Promote Mobility* >Provide a Natural Muscle Compound* >Revitalize Joints*

**52 week Nielsen ScanTrack data ending 6/30/12.

CONTAINS A NATURAL MUSCLE COMPOUND* HELP REVITALIZE YOUR JOINTS* KEY BUILDING BLOCK OF CARTILAGE*

2 PER DAY

ONLY 2 EASY-TO-SWALLOW CAPLETS help support cartilage and help with annoying flare-ups while supporting the cellular components within joints.* Starts Improving Joint Comfort in 7 Days*#

As a reminder, discuss the supplements and medications you take with your health care providers.

50972 01B B50972 LAB

40 POINTS

Osteo Bi-Flex(R) is manufactured under the highest standard for product quality, including purity and potency.

Every day joint cartilage breaks down and builds up. While we can’t reverse the aging process, we can take beneficial ingredients to comfort our joints.* Active joints need active joint...and muscle...support.** You work hard, play hard and demand a lot from your muscles and joints. Helping to keep them healthy now can help keep them healthy going forward as part of a continued joint care routine.* That’s why we created Osteo Bi-Flex(R) Joint & Muscle.

Every time you flex your knee, your muscles work together with your joints to make it happen.

Proud sponsor of the ARTHRITIS FOUNDATION(R)

Part No. 22-50972

Join the millions of people who choose Osteo Bi-Flex(R) for their joints every day, and have made it their #1 brand.

Metadata

Product Details

UPC / SKU0 30768 50972 9
DSLD Entry Date2014-02-26
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID30753
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.