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Hepagen

product on market Capsule Cardiovascular Research Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains milk thistle and N-acetyl-L-cysteine, which have moderate evidence for supporting liver function and detoxification. Thiamine and alpha-ketoglutarate contribute to metabolic processes, though overall evidence coverage for this specific combination is limited. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Hepagen
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3.75 mg (250% DV)
3.1× RDA — above typical dose 76 studies (A:0, B:33)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Liver, Freeze-Dried
100 mg
Alpha-Ketoglutarate
40 mg
N-Acetyl-L-Cysteine
30 mg
15 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
6.5 mg
Market median: 300.0mg (159 products)
4.2× RDA — above typical dose 76 studies (A:0, B:33)

Other Ingredients

Gelatin Garbanzo Bean Flour Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Directions Take one or two capsules per day, or as directed by a physician.

Formulation Notes

Hepagen is a scientifically-designed dietary supplement.

This is free of corn, soy, yeast, wheat, egg, milk and other common food allergens.

Gluten free, casein free

Additional Information

Ecological Formulas

Metadata

Product Details

UPC / SKU6 96859 13184 4
DSLD Entry Date2024-04-23
Product TypeOther Combinations
FormCapsule
BrandCardiovascular Research
DSLD ID304390
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.