Home/ Supplements/ Tryptophan/ L-Tryptophan 500 mg

L-Tryptophan 500 mg

product on market Capsule Doctor's Best Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for L-Tryptophan 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
90
Servings
Amino acid/Protein
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg
Market median: 500.0mg (70 products)

Other Ingredients

Hypromellose Microcrystalline Cellulose Calcium Laurate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested adult use: Take 1 capsule daily, or as recommended by a nutritionally informed physician. For optimum absorption, take separately from protein-containing foods and dietary supplements containing protein or amino acids.

Warnings & Precautions

Warning: Consult a physician before use if pregnant, nursing, taking medications, or have a medical condition.

May cause drowsiness.

Formulation Notes

L-Tryptophan provides this essential amino acid (protein building block) that is not synthesized by the body and must be obtained in the diet or supplementation.

It is also essential in the production of niacin, which is then metabolized into serotonin and melatonin in the brain. These neurotransmitters exert a calming effect and encourage better cognitive focus, a positive mood, and restful sleep. Helps exert a calming effect Helps encourage better cognitive focus, a positive mood, and restful sleep

Non-GMO/Gluten free/Soy free/Vegan

Non-GMO/Gluten free/Soy free/Vegan

Helps promote normal restful sleep, healthy mood and behavior

Additional Information

Store in a cool dry place.

Vegan

Metadata

Product Details

UPC / SKU7 53950 00126 8
DSLD Entry Date2024-01-24
Product TypeAmino acid/Protein
FormCapsule
DSLD ID302685
Data Updated2026-04-11
Research

Research Evidence

29
Research Sources
48
Avg Quality
19
Rct
5
Meta Analysis
3
Systematic Review
2
Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022 PubMed DOI
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023 PubMed DOI
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022 PubMed DOI
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021 PubMed DOI
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients PubMed DOI
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.