🟡 74/100

Review before taking

  • Zinc: 50mg is 1.2× the Tolerable Upper Intake Level (40mg)
  • B. subtilis: 47mg is 2.4× the Tolerable Upper Intake Level (20mg)
  • 67% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Zinc: 50mg is 1.2× the Tolerable Upper Intake Level (40mg)
⚠️ B. subtilis: 47mg is 2.4× the Tolerable Upper Intake Level (20mg)

The safety score is low because the amounts of zinc and B. subtilis in this supplement exceed the recommended maximum daily intake levels.

Label Data

1 Capsule(s) Serving Size
90 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (455% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.2× (UL: 40 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 50mg UL 40mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
47 mg
⚠️ Exceeds Tolerable Upper Intake Level by 2.4× (UL: 20 mg) 📚 2 studies — no high-quality reviews
This product: 47mg UL 20mg

Other Ingredients

Methylcellulose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (75% of products) Nutrient (48% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested use: Take 1 capsule daily with 8 ounces of water or your favorite beverage. May be taken with or without food.

⚠️ Warnings & Precautions

Made on equipment that also processes milk, eggs, fish, tree nuts and soy. This product is manufactured in a facility that processes fish.

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Please use caution if you have allergies or sensitivities to any of the listed ingredients.

Do not use if product has been opened or tampered with in any way. Keep out of reach of children and pets.

Keep out of reach of children and pets.

🧪 Formulation Notes

Made with Non GMO ingredients

Zinc/Copper + probiotics

Contains No Added: Milk, tree nuts, wheat, peanuts, or soy.

Additional Information

Good Manufacturing Practice cGMP Certified Lab Tested

Store in a cool, dry place.

Product Details

DSLD Entry Date 2023-10-24
Product Type Other Combinations
Form Capsule
Brand Amen
DSLD ID 298408
Data Updated 2026-04-11

Research Evidence

42 Research Sources
53 Avg Quality Score
20 Meta Analysis
10 Systematic Review
9 Rct
1 Observational
1 Regulatory Source
B Trace Elements and Risk of Immune-Mediated Skin Disease: A Systematic Review and Meta-analysis
Meta Analysis Nutrition reviews 2025
B Blood Trace Element Status in Multiple Sclerosis: a Systematic Review and Meta-analysis
Meta Analysis Biological trace element research 2022
B Micronutrient deficiency risk in long-term enterally fed patients: A systematic review
Systematic Review Clinical nutrition ESPEN 2022
B Essential Trace Element Status in Systemic Lupus Erythematosus: a Meta-analysis Based on Case-Control Studies
Meta Analysis Biological trace element research 2023
B Association between serum copper/zinc ratio and lung cancer: A systematic review with meta-analysis
Meta Analysis Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2022
B Vacuolated Marrow Cytopenias from Copper Deficiency to UBA1-Mutant VEXAS: Molecular Landscape, Systematic Review, and Cost-Efficient Diagnostic Algorithm
Systematic Review International journal of molecular sciences 2025
B Parenteral trace element provision: recent clinical research and practical conclusions
Systematic Review European journal of clinical nutrition 2016
B Copper Deficiency: A Frequently Overlooked Complication After MBS-A Systematic Review and Meta-analysis
Meta Analysis Obesity surgery 2025
B Copper in colorectal cancer patients: a systematic review and meta-analysis
Meta Analysis Carcinogenesis 2025
B Zinc deficiency and zinc/copper ratio imbalance in autism spectrum disorder: a reanalysis of six multinational studies
Meta Analysis Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2026
View all evidence for Copper →

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