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5-HTP 100 mg

product on market Capsule Foster Regal Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

L-5-Hydroxytryptophan and Valerian are supported by moderate evidence for mood and sleep support. Vitamin B6, Magnesium, and Niacin serve as essential cofactors for neurotransmitter synthesis. Overall, the evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (25% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
5 mg (250% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
50 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)

Other Ingredients

Calcium Phosphate Gelatin Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Start with a low dose of 1 capsule taken with a meal. Increase the dose slowly (every 3-5 days) up to a maximum of 4 capsules taken daily. Total daily intake should be divided into two or mode doses, with no more than 2 capsules per dose.

Warnings & Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Warning: This product should not be taken by children, pregnant or lactating women.

Warning: This product should not be taken by children, pregnant or lactating women.

May cause gastrointestinal upset, diarrhea or nausea which usually disappears by reducing dosage or is minimized by taking with food. As with any supplement, if discomfort persists discontinue use. Those suffering from gut disorders such as ulcers, irritable bowl disease, Crohn's disease, celiac disease, etc., should not use 5-HTP. Those using MAO-inhibitors, antidepressants and drugs containing fenfluramine should not use 5-HTP. May cause drowsiness. Do not use while driving or operating machinery.

Formulation Notes

5-HTP is the precursor to serotonin, a mood and appetite regulating neurotransmitter produced within the body. Combined with Valerian, Niacin, Magnesium and B-6, an important cofactor in the conversion to serotonin. Buffered to minimize any potential gastric discomfort.

Mfg. in a Ko Kosher Certified, FDA Registered Facility, using Good Mfg. Practices (GMPs)

Mfg. in a Ko Kosher Certified, FDA Registered Facility, using Good Mfg. Practices (GMPs)

USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Hydroxytryptophan with Valerian, Vitamin B-6, Niacin, & Magnesium Natural Griffonia Seed Extract Precursor to Serotonin

Gluten Free

Made in USA

Additional Information

Keep tightly closed. Store at room temperature: 59 degrees-86 degrees F (15 degrees to 30 degrees C).

Metadata

Product Details

DSLD Entry Date2023-08-23
Product TypeBotanical with Nutrients
FormCapsule
BrandFoster Regal
DSLD ID296988
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.