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SeroSyn

product on market Capsule Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 71% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines B vitamins and L-5-HTP, which have moderate evidence for supporting neurotransmitter synthesis and mood regulation. Chinese skullcap root extract is included for its potential calming effects, though clinical evidence for this specific botanical is more limited. Together, these ingredients target pathways associated with emotional balance and cognitive function.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for SeroSyn
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
90
Servings
Botanical with Nutrients
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Metafolin
555 mcg DFE (139% DV)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
Chinese Skullcap Root Extract
200 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)
80 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)

Other Ingredients

Hydroxypropylmethylcellulose Microcrystalline Cellulose Silica Stearic Acid
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one capsule three times daily with food or as directed by your healthcare practitioner.

Warnings & Precautions

Warning: Do not use if pregnant or nursing.

Caution: Not recommended for those under 18 years of age.

If taking antidepressant medication, particularly antidepressants such as MAO inhibitors or selective serotonin reuptake inhibitors (SSRIs), avoid use. If you have a medical condition - including symptomatic gastrointestinal disorders, or are taking medication - including over-the-counter cold medicine and high blood pressure medicines, consult your healthcare practitioner before use.

Use with caution when driving or operating machinery, may cause drowsiness.

Keep out of the reach of children.

Tamper evident: Do not use if safety seal is missing or broken.

Practitioner exclusive

Formulation Notes

SeroSyn features 5-HTP and theanine to support a positive mood and restful, relaxed state through beneficially modulating the metabolism of serotonin.

This product is non-GMO, gluten-free, and vegetarian.

This product is non-GMO, gluten-free, and vegetarian.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Support for a calm, positive mood

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 55571 93421 5
DSLD Entry Date2023-09-25
Product TypeBotanical with Nutrients
FormCapsule
BrandMetagenics
DSLD ID295858
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.