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Ostera

product on market Tablet or Pill Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Berberine and vitamin D are supported by moderate to strong evidence for supporting metabolic health and immune function. Vitamin K and iso-alpha acids have limited research regarding their specific synergistic effects in this formulation. The overall ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Ostera
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

12.5 mcg (63% DV)
Within RDA (0.8× RDA) 608 studies (A:16, B:251)
500 mcg (417% DV)
4.2× RDA — above typical dose 275 studies (A:9, B:175)
Reduced Iso-Alpha Acids Complex
370 mg
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose Calcium Silicate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended for use with Bone Builder - an advanced bioactive formulation for bone mineralization support.

Directions: Take one tablet twice daily, or as directed by your healthcare practitioner.

Warnings & Precautions

Warning: Do not use if pregnant, nursing, or taking cyclosporine. Caution: If taking medications consult your healthcare practitioner before use.

Keep out of the reach of children.

Practitioner exclusive

Formulation Notes

The scientifically advanced formula features selective kinase response modulators (SKRMs) in the form of RIAA, berberine, and vitamins D and K to help nutritionally support healthy bone remodeling during the aging process.

This product is non-GMO and gluten-free.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Promotes healthy bone remodeling in postmenopausal women

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 55571 91876 5
DSLD Entry Date2023-08-23
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID295850
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.