E-400 Selenium

product on market Tablet or Pill Metagenics 🟢 Safety: 100/100
Brand: Metagenics
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

298 mg (1787% DV)
📊 19.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 298mg UL 1000mg
Calcium
97 mg (7% DV)
74 mg (6% DV)
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 74mg UL 4000mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Silica Stearic Acid Magnesium Stearate Croscarmellose Sodium Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (79% of products) Nutrient (50% of products) Qualified Health (5% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take one tablet up to twice daily with meals or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: Keep out of the reach of children.

Tamper Evident: Do not use if safety seal is missing or broken.

Practitioner Exclusive

🧪 Formulation Notes

E-400 Selenium provides the essential trace mineral selenium and natural-source vitamin E, an antioxidant that helps protect tissues from damage caused by free radicals.

This product is non-GMO, gluten-free, and vegetarian.

This product is non-GMO, gluten-free, and vegetarian.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Antioxidant formula

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Product Details

UPC / SKU 7 55571 01500 6
DSLD Entry Date 2023-08-23
Product Type Other Combinations
Form Tablet or Pill
Brand Metagenics
DSLD ID 295675
Data Updated 2026-04-11

Research Evidence

273 Research Sources
55 Avg Quality Score
131 Meta Analysis
61 Systematic Review
55 Rct
19 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Other
1 Observational
1 Openfda Safety
A Selenium for preventing cancer
Meta Analysis The Cochrane database of systematic reviews 2018
PubMed DOI Cochrane
A Selenium supplementation for the primary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Selenium supplementation for critically ill adults
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011
PubMed DOI
B Selenium and prostate cancer: systematic review and meta-analysis
Meta Analysis The American journal of clinical nutrition 2012
PubMed DOI
B Selenium supplementation for Hashimoto's thyroiditis
Systematic Review The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
B Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI
B Selenium, antioxidants, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis The American journal of clinical nutrition 2020
PubMed DOI
B The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2017
PubMed DOI
B Meta-analysis of selenium effects on the meat quality of broilers
Meta Analysis Poultry science 2024
PubMed DOI
View all evidence for Selenium →

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