🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

8 Gram(s) Serving Size
60 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
30 Calorie(s)
📊 Market median: 5.0mg (298 products) 📚 701 studies (Tier A: 5, B: 123)
This product: 5mg
1 Gram(s)
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 1mg
0.75 Gram(s)
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 0.75mg

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (93% of products) Nutrient (20% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: Mix 1 scoop (8 g) daily with 8 oz of water or beverage of choice. For best results, take this product 30 minutes before exercise, or immediately following exercise with a recovery beverage such as Perfect Protein. For best results, take 4 servings daily for 1 week, followed by 1-2 servings daily. On rest days, take 1-2 servings daily with a meal or as directed by a trainer, coach, or healthcare professional.

⚠️ Warnings & Precautions

Warning: Not for use in patients with sever liver, kidney, cardiovascular disease, or bipolar disorder.

Caution: Do no use if pregnant or nursing.

Use below age of 18 only under the supervision of a healthcare practitioner.

If taking other dietary supplements or medications consult with your health professional prior to use.

Tamper evident: Do not use if safety seal is missing or broken.

Practitioner Exclusive

🧪 Formulation Notes

Expect more and get more with Creatine UP, featuring creatine, taurine, and betaine. Creatine can help keep you going strong by promoting lean muscle growth and muscle strength with exercise, both key support areas for athletes.

This product is non-GMO, gluten-free, and vegetarian.

This product is non-GMO, gluten-free, and vegetarian.

More Strength. More Muscle. Creatine promotes muscle strength with exercise

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten-Free gfco.org

Product Details

UPC / SKU 7 55571 95253 0
DSLD Entry Date 2023-07-18
Product Type Other Combinations
Form Powder
Brand Metagenics
DSLD ID 295670
Data Updated 2026-04-11

Research Evidence

739 Research Sources
47 Avg Quality Score
472 Clinical Trial
139 Meta Analysis
74 Systematic Review
47 Rct
2 Regulatory Source
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data
Meta Analysis JAMA psychiatry 2021
A HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis
Meta Analysis The Cochrane database of systematic reviews 2014
A Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease
Meta Analysis The Cochrane database of systematic reviews 2014
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack: a systematic review and network meta-analysis
Systematic Review BMC medicine 2019
B Efficacy of Creatine Supplementation Combined with Resistance Training on Muscle Strength and Muscle Mass in Older Females: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2021
B The Effects of Creatine Supplementation on Upper- and Lower-Body Strength and Power: A Systematic Review and Meta-Analysis
Meta Analysis Nutrients 2025
B Meta-analysis of the efficacy and safety of Finerenone in diabetic kidney disease
Meta Analysis Medicine 2026
B Creatine and creatine analogues in hypertension and cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2011
B HMG CoA reductase inhibitors (statins) for dialysis patients
Meta Analysis The Cochrane database of systematic reviews 2013
View all evidence for Creatine →

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