Chasteberry Plus by Metagenics — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Tablet(s) Serving Size

60 Servings

Botanical Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Chaste Tree fruit extract

100 mg

Black Cohosh (Actaea racemosa) root & rhizome extract

40 mg

📊 Market median: 80.0mg (136 products)

Median 80.0mg This product: 40mg

Ashwagandha (Withania somnifera) 15:1 root extract

60 mg

📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)

This product: 60mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Silica Stearic Acid Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (90% of products) Nutrient (7% of products)

Target Groups

Vegetarian Women (not pregnant or lactating) Girls: (All) Adult Female (18 - 50 Years) Seniors/Mature (>50 Years) - Women ONLY Gluten Free

Product Information

📋 Directions for Use

Directions: Take on tablet twice daily or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Do not use if pregnant or nursing. Caution: Consult your healthcare practitioner before use if you are taking medication or have a liver disorder or develop symptoms of liver trouble.

Keep out of reach of children.

Practitioner Exclusive

🧪 Formulation Notes

Chasteberry Plus combines chasteberry and black cohosh to help support menstrual regularity, ease menstrual cramps, and support reproductive health.

This product is non-GMO, gluten-free, and vegetarian.

Supports menstrual regularity, relieves menstrual discomfort

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Non-GMO Project Verified nongmoproject.org Certified Gluten-Free gfco.org

Product Details

UPC / SKU 7 55571 01345 3

DSLD Entry Date 2023-06-22

Product Type Botanical

Form Tablet or Pill

Brand Metagenics

DSLD ID 295662

Data Updated 2026-04-11

Research Evidence

63 Research Sources

54 Avg Quality Score

26 Systematic Review

21 Rct

11 Meta Analysis

5 Clinical Trial

B Identifying immunostimulatory herbal supplements that may flare autoimmune skin diseases: a systematic scoping review

Systematic Review Lupus science & medicine 2025

PubMed DOI

B Effects of Ashwagandha (Withania somnifera) on VO2max: A Systematic Review and Meta-Analysis

Meta Analysis Nutrients 2020

PubMed DOI

B Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Phytotherapy research : PTR 2022

PubMed DOI

B An update on the efficacy of anti-inflammatory agents for patients with schizophrenia: a meta-analysis

Meta Analysis Psychological medicine 2019

PubMed DOI

B Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysis

Meta Analysis Human psychopharmacology 2024

PubMed DOI

B Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis

Meta Analysis PloS one 2021

PubMed DOI

B Plant-derived nootropics and human cognition: A systematic review

Systematic Review Critical reviews in food science and nutrition 2023

PubMed DOI

B Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis

Meta Analysis Explore (New York, N.Y.) 2024

PubMed DOI

B Systematic review and network meta-analysis of the effects of plant active substance on quality of life in breast cancer patients

Systematic Review Frontiers in pharmacology 2025

PubMed DOI

B Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes

Systematic Review Annals of agricultural and environmental medicine : AAEM 2026

PubMed DOI

View all evidence for Ashwagandha →