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HexaNiacin

product on market Capsule Nature's Way Safety: 60/100
60/100

Review before taking

  • Niacin: 590mg is 16.9× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol management and cellular energy production, though research evidence for this specific formulation is limited. Due to a lower safety score, users should be aware of potential concerns such as flushing or liver enzyme elevations. Consult a professional regarding appropriate dosage.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 590mg is 16.9× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 590mg of Niacin, which is nearly 17 times higher than the recommended upper limit for daily intake.

Label

Product Label

Label for HexaNiacin
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

590 mg (3688% DV)
Exceeds UL by 16.9× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Hypromellose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Adults take 1 capsule three times daily, preferably with food.

Warnings & Precautions

Warning: Do not use if you are pregnant or nursing. If you have gallbladder disease, gout, diabetes, impaired liver function, a history of peptic ulcers, or if you are taking any medications, consult a healthcare professional before use.

Individuals with diabetes should monitor blood glucose levels while taking this product.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Formulation Notes

Supports cardiovascular function

Inositol hexaniacinate 590 mg per serving

Flush free

Gluten free. No wheat, yeast-derived ingredients, soy, dairy, or artificial colors, flavors, or preservatives.

Vegan

Additional Information

At Nature's Way, we strive to help people live their best lives, using the gifts of nature. To live up to that vision, we believe we need to care for the planet that provides those gifts. That's why the Nature’s Way square bottles use 97% post-consumer recycled plastic. We think it's one way to help care for the environment.

Questions? 1-800-9NATURE / naturesway.com

Bottles made from 97% post-consumer recycled plastic

Quality Global Sourcing Bottled & Tested In The USA

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Metadata

Product Details

UPC / SKU7 63948 05406 0
DSLD Entry Date2024-02-22
Product TypeVitamin
FormCapsule
DSLD ID293410
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.