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5-HTP (5-Hydroxytryptophan) 200 mg

product on market Capsule Protocol For Life Balance Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 83% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

5-HTP is supported by moderate evidence for improving mood and sleep quality. Vitamin B6 and Niacin act as essential cofactors in neurotransmitter synthesis, while glycine and taurine provide inhibitory support for relaxation. Overall, these ingredients have a well-documented safety profile in standard dosages.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP (5-Hydroxytryptophan) 200 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veg Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
83%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
2 mg (118% DV)
1.5× RDA — within safe limits 114 studies (A:3, B:35)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Glycine
100 mg
100 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Hypromellose Ascorbyl Palmitate Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: Take 1 capsule 1 to 2 times daily, preferably on an empty stomach before bedtime, or as directed by your healthcare practitioner.

Warnings & Precautions

Cautions/interactions: May cause mild, but transient GI discomfort. 5-HTP should be used with caution in combination with any serotonergic drug or herb, including SSRIs, MAOIs and St. John's wort. if you are taking any of these medications or if you are planning any surgical procedures, consult your healthcare practitioner prior to using this product. Not recommended for pregnant or nursing women.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Individuals with a history of cardiac conditions, use only under the direction of your healthcare practitioner.

Formulation Notes

How it works: 5-HTP is the intermediate precursor in the natural synthesis of serotonin, a neurotransmitter that helps to regulate mood, appetite, and sleep/wake cycles. 5-HTP readily crosses the blood-brain barrier and clinical studies suggest that 5-HTP can support healthy serotonin levels. Serotonin is associated with a positive mood and provides a substrate for the production of melatonin. This formula includes B-vitamins as cofactors, and is further enhanced with glycine, taurine, and inositol.

Supports a positive mood

With glycine, taurine & inositol

Non-GMO

Vegan/vegetarian

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Metadata

Product Details

UPC / SKU7 07359 10108 1
DSLD Entry Date2023-06-22
Product TypeOther Combinations
FormCapsule
DSLD ID292250
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.