🟡 60/100

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  • Folate: 5000mg is 5000.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 5000mg is 5000.0× the Tolerable Upper Intake Level (1.0mg)

This product received a low safety score because the amount of folate it contains significantly exceeds the recommended maximum daily limit.

Label Data

1 Vegetarian Capsule(s) Serving Size
60 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

5000 mcg DFE (1250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 5000.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 5000mg UL 1.0mg

Other Ingredients

Rice Concentrate Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, adults take 1 capsule per day, or as directed by your health care practitioner.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dosage.

Please consult a physician before consuming this product if you are pregnant or nursing, taking medication or have a medical condition.

Not intended for use by individuals under the age of 18.

Do not use if safety seal is damaged or missing.

Keep out of reach of children.

🧪 Formulation Notes

5-MTHF is a methylated from folate. Unlike other folates, 5-MTHF contains the active form of folate naturally present in the body. This form supports absorption and has a greater bioavailability for those who need it most. Superior Labs 5-MTHF capsules contain 5,000 mcg DFE 5-MTHF, with absolutely no magnesium stearate, dioxides, preservatives, or other potentially harmful ingredients of any kind.

Superior Labs 5-MTHF capsules contain 5,000 mcg DFE 5-MTHF, with absolutely no magnesium stearate, dioxides, preservatives, or other potentially harmful ingredients of any kind.

This product is formulated, developed and manufactured in a FDA registered and GMP certified facility, 3rd party inspected by a leading compliance authority for superior quality assurance.

100% pure Pure and potent Advanced absorption Methylated for superior bioavailability Cardiovascular & neurological health Cognition & mood

Does not contain: Magnesium stearate, dioxides, preservatives, or artificial ingredients of any kind.

Additional Information

Store in a cool, dry place.

Metal Safe Heavy Metal Tested Made in USA GMP certified facility

Product Details

UPC / SKU 8 505069 00663 6
DSLD Entry Date 2023-06-22
Product Type Vitamin
Form Capsule
Brand SuperiorLabs
DSLD ID 286827
Data Updated 2026-04-11

Research Evidence

363 Research Sources
57 Avg Quality Score
187 Meta Analysis
56 Systematic Review
54 Rct
29 Guideline
26 Clinical Trial
6 Cochrane Review
2 Regulatory Source
1 Other
1 Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025
View all evidence for Folate →

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