🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
50 mcg (250% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
Sodium
20 mg (1% DV)
1500 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1500mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 100mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 275mg

Other Ingredients

Cellulose Crospovidone Guar Gum Magnesium Silicate Maltodextrin Medium Chain Triglycerides Polydextrose Silica Titanium Dioxide Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: For adults, take two (2) tablets per day, preferably with meals.

⚠️ Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Contains shellfish (crab, crayfish, lobster, shrimp) ingredients.

🧪 Formulation Notes

Helps maintain healthy bones & supports a healthy immune system

Based on two human studies with 5-LOXIN Advanced extract where subjects rated their joint health over time, subjects' joint health improved within 7 days, and continued to improve throughout the duration of the studies. This product contains 50 mcg of vitamin D, which is equivalent to 2,000 IU.

Made in the USA with select ingredients from around the world.

Triple Strength Joint Soother Glucosamine Boswellia + Vitamin D With 5-LOXIN Advanced

Shows improvement in joint comfort within 7 days

Triple Strength Refers to level of Glucosamine HCl per tablet compared to item number 44772.

Additional Information

Store at room temperature.

Individual results may vary.

To reorder item # 25686 www.puritan.com 1-800-645-1030

QA Quality Assured

Product Details

UPC / SKU 0 25077 00082 1
DSLD Entry Date 2023-06-22
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 286485
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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