Home/ Supplements/ Vitamin C/ Ester-C 1000 mg plus D3 125 mcg (5000 IU...

Ester-C 1000 mg plus D3 125 mcg (5000 IU)

product on market Tablet or Pill Puritan's Pride Safety: 87/100
87/100

This product is generally safe

  • Vitamin D: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C and D3 are supported by strong evidence for immune function and bone health maintenance. Calcium further supports skeletal integrity, though overall evidence coverage for this specific formulation is limited. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D: 0.125mg is 1.2× the Tolerable Upper Intake Level (0.1mg)

Label

Product Label

Label for Ester-C 1000 mg plus D3 125 mcg (5000 IU)
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
1000 mg (1111% DV)
125 mcg (625% DV)
Exceeds UL by 1.2× (UL: 0.1 mg) 608 studies (A:16, B:251)
Calcium
111 mg (9% DV)

Other Ingredients

Cellulose Calcium Silicate Maltodextrin natural Palm leaf glaze Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) tablet daily, preferably with a meal.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Formulation Notes

Ester-C A unique gentle form of vitamin C

Ester-C plus D3 1000 mg Non-Acidic Ester-C 125 mcg (5000 IU) Vitamin D3

24 hour immune support

Additional Information

Store at room temperature.

To reorder item # 25870 www.puritan.com 1-800-645-1030

QA Quality Assured

Made in the USA with select ingredients from around the world.

Metadata

Product Details

UPC / SKU0 25077 00084 5
DSLD Entry Date2023-06-22
Product TypeOther Combinations
FormTablet or Pill
DSLD ID286297
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
Compare

Similar Products

View all Vitamin C products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.