Methyl-Guard
90/100
This product looks safe
- Folate: 2mg is 2.0× the Tolerable Upper Intake Level (1.0mg)
- 75% of ingredients have research evidence
C
Label Compliance Grade
Product Label
Have a supplement label? Find it here.
Upload a photo of any supplement label to search our database of 92,312 products.
Safety Alerts
⚠️ Folate: 2mg is 2.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
3 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Supplement Facts — Evidence Check
20.4 mg
(1200% DV)
📊 15.7× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
2 mg DFE
(500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
1.2 mg
(50000% DV)
📊 500.0× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
1.8 Gram(s)
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Other Ingredients
Hypromellose
Silicon Dioxide
Calcium Citrate
Calcium Laurate
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (98% of products)
Structure/Function (89% of products)
Nutrient (43% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Suggested use: Take 3 capsules two times daily or as recommended by your health-care practitioner.
⚠️ Warnings & Precautions
Tamper evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
🧪 Formulation Notes
Heart/Vessels Mood
Gluten free
Methylation Factors
This product uses Gnosis S.p.A.’s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic).
Additional Information
Store tightly sealed in a cool, dry place.
Manufactured in the USA using US & imported ingredients
Product Details
Research Evidence
153
Research Sources
55
Avg Quality Score
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A
Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
A
Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
B
Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
B
The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Compare Similar Products
Water Ease
Designs for Health
100
Mag Aspartate
Karuna
100
Vitamin B-6 50 mg
Kirkman
100
Neuro-Balance 620 Milligrams
Montiff
100
Vitamin B-6 50 Milligrams
NutraBio
100