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Somnolin

product on market Tablet or Pill Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

This formula combines B vitamins with L-theanine and 5-HTP to support neurotransmitter synthesis and relaxation. Moderate evidence suggests these ingredients may assist with sleep quality and mood regulation. However, overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Somnolin
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

40 mg (2000% DV)
30.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
500 mcg (8334% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)

Other Ingredients

Microcrystalline Cellulose Cellulose Stearic Acid Croscarmellose Sodium Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: Take two tablets daily or as directed by your healthcare practitioner. May be taken during the day or before bedtime.

Warnings & Precautions

WARNING: Do not use if pregnant or lactating.

CAUTION: Not recommended for those under 18 years of age.

If taking antidepressant medication, particularly antidepressants such as MAO inhibitors or selective serotonin reuptake inhibitors (SSRIs), avoid use. If you have a medical condition, or are taking medication-including over-the-counter cold medicine, consult your healthcare practitioner before use.

Use with caution when driving or operating machinery, may cause drowsiness.

Keep out of the reach of children.

Formulation Notes

Vegetarian

Additional Information

Genetic Potential Through Nutrition

5-MTHF BODY-READY FOLATE

Support for Serotonin Function

LSM004E1

PROD. SOMN60

Metadata

Product Details

UPC / SKU7 55571 91345 6
DSLD Entry Date2013-11-25
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID27873
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.