Somnolin

product on market Tablet or Pill Metagenics 🟢 Safety: 100/100
Brand: Metagenics
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

40 mg (2000% DV)
📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 40mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
500 mcg (8334% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
200 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 200mg
200 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 200mg

Other Ingredients

Microcrystalline Cellulose Cellulose Stearic Acid Croscarmellose Sodium Silica

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take two tablets daily or as directed by your healthcare practitioner. May be taken during the day or before bedtime.

⚠️ Warnings & Precautions

WARNING: Do not use if pregnant or lactating.

CAUTION: Not recommended for those under 18 years of age.

If taking antidepressant medication, particularly antidepressants such as MAO inhibitors or selective serotonin reuptake inhibitors (SSRIs), avoid use. If you have a medical condition, or are taking medication-including over-the-counter cold medicine, consult your healthcare practitioner before use.

Use with caution when driving or operating machinery, may cause drowsiness.

Keep out of the reach of children.

🧪 Formulation Notes

Vegetarian

Additional Information

Genetic Potential Through Nutrition

5-MTHF BODY-READY FOLATE

Support for Serotonin Function

LSM004E1

PROD. SOMN60

Product Details

UPC / SKU 7 55571 91345 6
DSLD Entry Date 2013-11-25
Product Type Other Combinations
Form Tablet or Pill
Brand Metagenics
DSLD ID 27873
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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