🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
60 Servings
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 460mg

Other Ingredients

Cellulose Di-Calcium Phosphate Stearic Acid Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommended use: Take 1 tablet in the morning and one in the evening with water for all-day, all-night support.

⚠️ Warnings & Precautions

Warning: Do not use St. John's Wort while taking any prescription drugs without the advice of your prescribing physician. Do not use with prescription antidepressants, contraceptives, immunosuppressants, anticoagulants, Digoxin, blood thinners, or medications for HIV, epilepsy, or cancer.

Avoid excessive exposure to UV radiation (e.g. sunlight, tanning).

Not recommended for use by pregnant or lactating women.

Keep out of the reach of children.

Do not use if inner seal is missing or damaged.

🧪 Formulation Notes

Nervous system support

Herbal extract

Supports emotional balance and well-being

Guaranteed pure

Standardized hypericin

Additional Information

Bottle made from 100% post consumer recycled material. We are committed to you and our planet. Scan to learn more.

New look Same great product

Product Details

UPC / SKU 0 99904 00653 9
DSLD Entry Date 2022-10-24
Product Type Botanical
Form Tablet or Pill
DSLD ID 278279
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
View all evidence for St Johns Wort →

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