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ProSoothe II

product on market Capsule Pure Encapsulations Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 62% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains essential vitamins and minerals, including magnesium and calcium, which are supported by strong evidence for maintaining bone health and neuromuscular function. Vitamin D and E provide antioxidant support and immune regulation. Overall, these ingredients are well-researched, though the specific evidence coverage for this formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for ProSoothe II
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Botanical with Nutrients
Product Type
62%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mcg (50% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
134 mg (893% DV)
8.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
33 mg (1941% DV)
25.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
100 mg (8% DV)
100 mg (24% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
Chaste Tree fruit extract
200 mg
Relora Patented Proprietary Blend
270 mg
Market median: 300.0mg (122 products) 22 studies (A:0, B:7)

Other Ingredients

Cellulose Water Modified Food and Corn Starch Ascorbyl Palmitate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 2 capsules, 1-2 times daily, with meals. May be used daily or during the luteal phase only, as directed by your health professional.

Warnings & Precautions

Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, particularly psychiatric medication, consult your health professional before use. Do not use concurrently with antidepressants.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Certified Gluten-free by the Gluten-Free Certification Organization, www.gluten.org

Supports menstrual comfort and mood

Gluten-free, non-GMO & hypoallergenic

Gluten-free, non-GMO & hypoallergenic

Additional Information

Store in a cool, dry place.

Scan to learn about our hypoallergenic supplements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 66298 01297 1
DSLD Entry Date2022-11-22
Product TypeBotanical with Nutrients
FormCapsule
BrandPure Encapsulations
DSLD ID278259
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.