Glucosamine Chondroitin by Sundown Naturals — Ingredients, Evidence & Safety

Product Label

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Label Data

3 Caplet(s) Serving Size

40 Servings

Other Combinations Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Carbohydrates

2 Gram(s) (1% DV)

Vitamin C

300 mg (333% DV)

Vitamin D

3.7 mcg (19% DV)

✅ Within RDA (0.2× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.0037mg UL 0.1mg

Calcium

200 mg (15% DV)

Manganese

5 mg (217% DV)

✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews

RDA 2.3mg This product: 5mg UL 11mg

Sodium

35 mg (2% DV)

Glucosamine Chondroitin Complex

2400 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 2400mg

Other Ingredients

Vegetable Magnesium Stearate Silica Vegetable Cellulose Crospovidone Beet Juice

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: For adults, take three (3) caplets daily, preferably with a meal.

⚠️ Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

Warning: If you are pregnant, nursing, taking any medications, including blood thinners, or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper Resistant: Do not use if seal under cap is broken or missing.

Contains shellfish (crab, shrimp) ingredients.

🧪 Formulation Notes

Smart facts Naturally sourced colors

No preservatives

Contains Calcium & Vitamin D3

Non-GMO. No gluten, no wheat, no milk, no lactose, no artificial flavor, no artificial sweetener, no preservatives, no sugar, no soy, no yeast.

Made in the USA with select ingredients from around the world

100% free of No dairy/lactose No artificial flavors Non-GMO GF Certified Gluten-free

Additional Information

Individual results may vary.

Store at room temperature and avoid excessive heat.

Supports joint mobility & flexibility

GF Certified Gluten-free

Questions? Call toll free 1-888-VITAHELP (848-2435) or visit us at www.sundownnaturals.com

Product Details

UPC / SKU 0 30768 03749 9

DSLD Entry Date 2022-10-24

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand Sundown Naturals

DSLD ID 277483

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →