5-MTHF
60/100
Review before taking
- Folate: 1700mg is 1700.0× the Tolerable Upper Intake Level (1.0mg)
- 100% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 1700mg is 1700.0× the Tolerable Upper Intake Level (1.0mg)
The safety score is low because the amount of folate in this supplement is 1,700 times higher than the recommended maximum daily limit.
Label Data
1 Capsule(s)
Serving Size
120
Servings
Vitamin
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
1700 mcg DFE
(425% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1700.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
Other Ingredients
Rice Chelate
Gelatin
Water, Purified
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Recommendations: Take one (1) capsule daily, or as directed by your physician.
⚠️ Warnings & Precautions
Warning: If you are pregnant or breast feeding, consult your physician before using this product.
Keep out of reach of children.
For professional use only.
🧪 Formulation Notes
Contains no preservatives.
(6S)-5-Methyltetrahydrofolic acid
Non-GMO
Additional Information
Keep container tightly closed, store in a cool, dry place.
Bisphenol-A (BPA) & Phthalate Free
GMP Certified
Product Details
UPC / SKU
8 15354 02179 9
DSLD Entry Date
2023-05-24
Product Type
Vitamin
Form
Capsule
DSLD ID
277332
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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