🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
1000 mg (1667% DV)
Calcium
110 mg (11% DV)
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 102mg

Other Ingredients

Vegetable Cellulose Calcium Silicate natural Palm leaf glaze Magnesium Stearate Stearic Acid

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take one (2) tablets once daily, preferably with a meal.

2 per day

⚠️ Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

🧪 Formulation Notes

Non-GMO. No gluten, no wheat, no milk, no lactose, no artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no soy, no yeast, no fish. Sodium free.

Suitable for Vegetarians.

Patented immune health formula

Plus, Ester-C is manufactured without chemicals to neutralize pH, which means it’s non-acidic and gentle on your stomach.

Patented Ester-C delivers 24-hour immune and antioxidant support...so one serving a day is all you need.

Clinically studied to last longer than regular Vitamin C

Ester-C lasts longer than regular Vitamin C and supports your immune system for 24 hours!

Enjoy the benefits of Ester-C every day! Patented 24 hour immune support Clinically studied to stay in the immune system longer than regular vitamin C Non-acidic and gentler on your stomach than regular Vitamin C

Additional Information

Store at room temperature.

Made in the USA with select ingredients from around the world

Ester-C is the patented immune health formula that stays in your system for 24 hours – so you have the kind of support you can count on 24/7. Ester-C is carefully formulated to contain naturally occurring metabolites. Metabolites are substance derived from other compounds (such as nutrients) during the process of metabolism. The metabolites in Ester-C help enhance the retention of Vitamin C by your white blood cells, which are a vital component of your immune system. So once you take your daily dose of Ester-C, it gets into your white blood cells, and stays there – for up to 24 hours, clinically studied to last longer than regular Vitamin C.

Ester-C has been clinically studied to stay in the white blood cells for up to 24 hours, which is longer than regular Vitamin C. White blood cells are an important component of the immune system

Stomach friendly!

Not all Vitamin C is created equal...There is only one patented Ester-C formula

Call toll free 1-866-417-0739 with questions or comments, Mon.-Sat., 9am-7pm EST.

Product Details

DSLD Entry Date 2022-09-22
Product Type Other Combinations
Form Tablet or Pill
Brand NatureSmart
DSLD ID 277268
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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