Home/ Supplements/ Vitamin B6/ Rest & Renew

Rest & Renew

product on market Capsule LES Labs Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 86% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines magnesium, L-theanine, and ashwagandha, which have moderate to strong evidence for supporting relaxation and sleep quality. Vitamin B6 and 5-HTP are included to support neurotransmitter synthesis. Research suggests these ingredients generally promote a calming effect on the nervous system.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Rest & Renew
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
86%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (294% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
30 mg (7% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)
100 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
Market median: 100.0mg (108 products)
0.3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Hypromellose Rice Bran powder
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take one (1) capsule daily before sleep or as directed by a healthcare practitioner.

Warnings & Precautions

Caution: Keep out of reach of children.

Pregnant or lactating women and those undergoing treatment for a medical condition should consult a physician before taking this supplement.

Do not use if outer seal is missing or damaged.

Formulation Notes

Made with non-GMO ingredients

Dietary Supplement with 5-HTP & Phosphatidylserine

Promotes restful sleep & rejuvenation Helps reduce stress & promotes relaxation Supports a healthy sleep-wake cycle

Additional Information

Store in a dry, cool place.

Manufactured in the USA cGMP Certified Manufacturing

Metadata

Product Details

UPC / SKU6 02573 11489 6
DSLD Entry Date2022-10-24
Product TypeOther Combinations
FormCapsule
BrandLES Labs
DSLD ID276528
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
Compare

Similar Products

Water Ease
Designs for Health · Capsule
100
Mag Aspartate
Karuna · Capsule
100
Vitamin B-6 50 mg
Kirkman · Capsule
100
Neuro-Balance 620 Milligrams
Montiff · Capsule
100
Vitamin B-6 50 Milligrams
NutraBio · Capsule
100
View all Vitamin B6 products →
Vitamin B6 research Best Vitamin B6 All Vitamin B6 products More from LES Labs View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.