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Nicotinamide 500 mg

product on market Capsule NusaPure Safety: 80/100
80/100

This product is generally safe

  • Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Nicotinamide is a form of vitamin B3 supported by strong evidence for cellular energy metabolism and skin health. Polygonum cuspidatum extract contains resveratrol, which has moderate evidence for supporting antioxidant activity. Overall, the evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Nicotinamide 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
180
Servings
Botanical with Nutrients
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
Polygonum cuspidatum extract
100 mg

Other Ingredients

Cellulose Silica Magnesium Stearate Rice Flour powder
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take one capsule daily, preferably with a meal or as directed by a healthcare professional.

Warnings & Precautions

Caution: For adults only.

Not to be used by pregnant/lactating women or those with liver problems, stomach ulcers or diabetes unless recommended by your healthcare practitioner.

Not manufactured with sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or preservatives. Produced in a GMP facility that processes other ingredients containing these allergens.

Do not use if safety seal is damaged or missing. Do not eat freshness packet.

Keep out of reach of children.

Formulation Notes

Not manufactured with sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or preservatives.

Premium quality Assembled in USA

GMO free Made with non-GMO Ingredients Gluten free FDA registered facility

Nicotinamide 500 mg Enhanced with resveratrol

Nicotinamide (vitamin B-3) is a form of niacin that plays a role in energy metabolism. Nicotinamide is a good source of vitamin B-3 with a lower flushing effect than that of niacin.

Assembled in USA

Natural

Supports cellular energy production Supports healthy cell repair Supports healthy aging

Natural color variation may occur in this product.

Additional Information

Store in a cool, dry place.

Manufactured in a cGMP Inspected Facility

Metadata

Product Details

UPC / SKUX002B17DEN
DSLD Entry Date2022-11-22
Product TypeBotanical with Nutrients
FormCapsule
BrandNusaPure
DSLD ID274991
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.