🟢 80/100

This product is generally safe

  • Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label Data

1 Veggie Capsule(s) Serving Size
180 Servings
Botanical with Nutrients Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

500 mg (3125% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg
Polygonum cuspidatum extract
100 mg

Other Ingredients

Cellulose Silica Magnesium Stearate Rice Flour powder

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take one capsule daily, preferably with a meal or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Caution: For adults only.

Not to be used by pregnant/lactating women or those with liver problems, stomach ulcers or diabetes unless recommended by your healthcare practitioner.

Not manufactured with sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or preservatives. Produced in a GMP facility that processes other ingredients containing these allergens.

Do not use if safety seal is damaged or missing. Do not eat freshness packet.

Keep out of reach of children.

🧪 Formulation Notes

Not manufactured with sugar, salt, starch, yeast, wheat, gluten, corn, soy, milk, egg, shellfish or preservatives.

Premium quality Assembled in USA

GMO free Made with non-GMO Ingredients Gluten free FDA registered facility

Nicotinamide 500 mg Enhanced with resveratrol

Nicotinamide (vitamin B-3) is a form of niacin that plays a role in energy metabolism. Nicotinamide is a good source of vitamin B-3 with a lower flushing effect than that of niacin.

Assembled in USA

Natural

Supports cellular energy production Supports healthy cell repair Supports healthy aging

Natural color variation may occur in this product.

Additional Information

Store in a cool, dry place.

Manufactured in a cGMP Inspected Facility

Product Details

UPC / SKU X002B17DEN
DSLD Entry Date 2022-11-22
Product Type Botanical with Nutrients
Form Capsule
Brand NusaPure
DSLD ID 274991
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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