🟡 60/100

Review before taking

  • Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

The safety score is low because the amount of niacin in this supplement significantly exceeds the recommended daily upper limit of 35mg.

Label Data

1 Veggie Capsule(s) Serving Size
200 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

400 mg (2500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 11.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 400mg UL 35mg
100 mg (625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg

Other Ingredients

Cellulose Silica Magnesium Stearate Rice powder

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: For adults, take one (1) capsule daily preferably with a meal. Do not exceed one capsule per day.

⚠️ Warnings & Precautions

Do not exceed one capsule per day.

Warning: For adults only.

Not for use by pregnant or lactating women. Consult your doctor before using if you have or have had any health condition (liver problems, stomach ulcers, diabetes, gout, etc.), or if you are taking any medications or remedies including OTC medications, or are planning any medical procedure.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Allergen Information: Contains no artificial coloring, artificial flavors, yeast, corn, milk, or milk derivatives, lactose, salt, sodium, gluten, egg, wheat, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Discontinue use and consult your doctor if any adverse reactions occur, such as gastrointestinal discomfort or any allergic reaction.

🧪 Formulation Notes

GMO Free Made with Non-GMO Ingredients Gluten Free FDA Registered Facility

Assembled in USA Tested Cardiovascular support Promotes healthy energy metabolism Supports nervous system & energy production Supports blood vessel health Max Strength

Allergen Information: Contains no artificial coloring, artificial flavors, yeast, corn, milk, or milk derivatives, lactose, salt, sodium, gluten, egg, wheat, fish, shellfish or tree nut ingredients.

Additional Information

Store in a cool dry place. Avoid excessive heat or moisture.

Premium Quality Assembled in USA Gluten Free FDA Registered Facility

Manufactured in a cGMP Inspected Facility

Product Details

UPC / SKU X001WS06UT
DSLD Entry Date 2022-11-22
Product Type Vitamin
Form Capsule
Brand NusaPure
DSLD ID 274950
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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