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Joint Complex

product on market Capsule Professional Botanicals Safety: 87/100
87/100

This product is generally safe

  • Manganese: 12mg is 1.1× the Tolerable Upper Intake Level (11mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are commonly used to support joint structure and function, though research evidence for their efficacy remains mixed. Vitamin C and magnesium salicylate provide antioxidant and anti-inflammatory support. Overall, the clinical evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Manganese: 12mg is 1.1× the Tolerable Upper Intake Level (11mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Joint Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
MSM
250 mg
Market median: 1000.0mg (2 products)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
Vitamin C
115 mg (200% DV)
Vitamin C
30 mg (50% DV)
Calcium
40 mg (4% DV)
15 mg (4% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
30 mg (8% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
3.5 mg (25% DV)
Within RDA (0.3× RDA) 263 studies (A:6, B:134)
12 mg (600% DV)
Exceeds UL by 1.1× (UL: 11 mg) 9 studies — no high-quality reviews
Proprietary Blend
148 mg

Other Ingredients

Vegetable Capsule
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Dosage: Adults or children 12 or more years of age, take two capsules two times a day, or as directed.

Warnings & Precautions

Consult a physician if pregnant, nursing or allergic to aspirin.

Consult a physician if pregnant, nursing or allergic to aspirin.

Warning: (California) Cancer & Reproductive Harm www.P65Warnings.ca.gov.

Keep out of reach of children.

Formulation Notes

Supports the maintenance of healthy joints, tendons, elasticity and cartilage.

EDS: Added enzymes for better absorption & breakdown. AdPT: Adaptogenic herbs for energy production & adaptation.

Gluten free Non GMO No fillers 3x tested

Premium quality

Additional Information

Gluten free Non GMO

Made in USA

2 Please recycle

Est. 1980

Metadata

Product Details

UPC / SKU8 98175 00161 4
DSLD Entry Date2022-10-24
Product TypeOther Combinations
FormCapsule
BrandProfessional Botanicals
DSLD ID274321
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.