🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s)
10 mg (588% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 200mg
20 mg
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 20mg
20 mg
📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)
This product: 20mg

Other Ingredients

Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide Hypromellose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, take two (2) capsules once daily, with at least 8 oz. of water or as directed by a healthcare professional. Do not exceed recommended dosage in 24 hour period.

⚠️ Warnings & Precautions

Keep out of reach of children.

Caution: Do not use if pregnant or nursing.

Do not exceed recommended dosage in 24 hour period. Do not exceed recommended dose.

If you are taking any medication or are under the care of a physician for depression or related disorder, contact your physician before using this product.

May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Product has been manufactured at a cGMP facility.

5-HTP Plus With co-factor B6

Plus serotonin synthesizers

Supports brain function, mood & sleep

Vegan friendly

Gluten free

Additional Information

Store in a cool, dry place.

30-day supply

Manufactured in the USA

Product Details

UPC / SKU 8 50002 95620 7
DSLD Entry Date 2022-08-23
Product Type Other Combinations
Form Capsule
DSLD ID 272247
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

Compare Similar Products

View all 5 Htp products →