Triple Flex Triple Strength by Nature Made — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Caplet(s) Serving Size

60 Servings

Other Combinations Product Type

50% Evidence Coverage

Supplement Facts — Evidence Check

Sodium

75 mg (3% DV)

Glucosamine Hydrochloride

1.5 Gram(s)

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 1.5mg

Chondroitin Sulfate Sodium

800 mg

📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)

This product: 800mg

Methysulfonylmethane

750 mg

Other Ingredients

Glucosamine Hydrochloride Chondroitin Sulfate Sodium Bovine Porcine Avian Methylsulfonylmethane Water Hypromellose Color added Silicon Dioxide Magnesium Stearate Medium Chain Triglycerides Inulin

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: Adults, take 2 caplets daily with water and a meal. Take 4-6 weeks to see results. Results may vary.

⚠️ Warnings & Precautions

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant, nursing, taking medication, or allergic to shellfish, consult your physician before use.

Contains: Shellfish (shrimp & crab).

🧪 Formulation Notes

Joint support formula

Per serving: Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg

No synthetic dyes - color derived from natural source No artificial flavors No preservatives Gluten free

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org

Additional Information

#1 Pharmacist recommended Vitamin & supplement brand

USP Verified Dietary Supplement

Store tightly closed, in a cool, dry place, out of reach of children.

Product Details

DSLD Entry Date 2022-06-16

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand Nature Made

DSLD ID 271076

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →