🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
90 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

5 mg (250% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
1000 mcg (16666% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg
25 mcg (8.3% DV)
✅ Within RDA (0.8× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.025mg

Other Ingredients

Mannitol natural Cherry flavor Vegetable Stearic Acid Vegetable Cellulose L-Ascorbic Acid Vegetable Magnesium Stearate Silica Stevia

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take 1 or 2 tablets daily. Allow tablet to dissolve under tongue.

⚠️ Warnings & Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

🧪 Formulation Notes

Gluten free

Sublingual

With B-6, Folate & Biotin

Nutritionally supports healthy nervous system and cardiovascular function

Vegetarian/vegan

Methylcobalamin is the form of B-12 active in the central nervous system. The liver may not convert cyanocobalamin, the common supplement form of vitamin B-12, into adequate amounts of methylcobalamin the body may need.

FDA Registered Facility (Reg. #1023013) Mfg. Under Good Manufacturing Practices (GMPs) Conforms to USP <2091> for weight.

Made in USA

Additional Information

Quali Pure

Keep tightly closed. Store at room temperature: 59 degrees-86 degrees F (15 degrees to 30 degrees C).

Product Details

DSLD Entry Date 2022-02-23
Product Type Vitamin
Form Tablet or Pill
DSLD ID 266678
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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