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Folgard RX Tablets

product on market Tablet or Pill Upsher-Smith Safety: 87/100
87/100

This product is generally safe

  • Folic Acid: 2.2mg is 2.2× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Folic acid, vitamin B6, and vitamin B12 are supported by strong evidence for supporting neurological function and red blood cell formation. These nutrients play critical roles in homocysteine regulation and DNA synthesis. Research indicates these ingredients are generally safe and effective for addressing specific nutritional deficiencies.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folic Acid: 2.2mg is 2.2× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Folgard RX Tablets
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2.2 mg
Exceeds UL by 2.2× (UL: 1.0 mg) 226 studies (A:10, B:105)
25 mg
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
416.7× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Dibasic Calcium Phosphate Carnauba Wax Citric Acid FD&C Blue #2 Aluminum Lake FD&C Red #40 Aluminum Lake FD&C yellow #5/tartrazine aluminum lake Hypromellose Magnesium Stearate Microcrystalline Cellulose modified Food Starch Polyethylene Glycol Polysorbate 80 Silicon Dioxide Sodium Citrate Sodium Starch Glycolate Stearic Acid Titanium Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Usual Dose: Adults - one tablet daily or as directed by a physician.

Warnings & Precautions

Precautions: Folic Acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations remain progressive.

This product contains FD&C Yellow #5 (tartrazine) which may cause allergic-type reactions (including bronchial asthma) in certain susceptible persons. Although the over-all incidence of FD&C Yellow #5 (tartrazine) sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity.

Keep out of reach of children.

Formulation Notes

Contains color additives including FD&C Yellow #5 (tartrazine).

2.2 mg Folic Acid, 25 mg Vitamin B-6, 1 mg Vitamin B-12, Combination

With 1 mg B-12

Additional Information

Rx only

Store at controlled room temperature, 15-30(0)C (59-86(0)F). Protect from light and moisture. Dispense in tight container with a child-resistant closure.

9C878 KU F2 R0213

N

Metadata

Product Details

UPC / SKU3 0245-0191-11 7
DSLD Entry Date2013-10-25
Product TypeVitamin
FormTablet or Pill
BrandUpsher-Smith
DSLD ID26627
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
View all evidence for Folate →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.