Home/ Supplements/ Niacin/ Niacin 250 mg

Niacin 250 mg

product on market Capsule Time Cap Labs Safety: 60/100
60/100

Review before taking

  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol levels and cardiovascular health, with strong clinical evidence for these effects. However, the safety score of 60 indicates potential concerns, as high doses may cause flushing or liver enzyme elevations. Evidence coverage for this specific formulation is very limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin is more than seven times the recommended upper limit for daily intake.

Label

Product Label

Label for Niacin 250 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
100
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg (1250% DV)
Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Sugar Shellac Gelatin Corn Starch Talc FD&C Green #3 Turmeric FD&C Yellow #6 Riboflavin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults only: One capsule daily as a dietary supplement.

Warnings & Precautions

Do not take more than this amount unless directed by a physician.

Warning: Do not use this product if you have a known sensitivity or allergy to niacin.

Use only under the advice and supervision of a physician if you: have heart disease, recurrent chest pain (angina), or recently suffered a heart attack are taking high blood pressure or cholesterol-lowering drugs (because of possible drug interactions) have any of the following conditions: gallbladder disease, gout, arterial bleeding, diabetes, impaired liver function, peptic ulcer, or are a pregnant or lactating woman

Keep out of the reach of children.

If you are pregnant or nursing a baby, seek the advice of a health professional before using this product

Caution: Niacin may cause temporary flushing, itching and tingling, feelings of warmth and headache, particularly when beginning, increasing dose, or changing brand of niacin. these effects seldom require discontinuing niacin use. Skin rash, upset stomach, and low blood pressure when standing are less common symptoms; if they persist, contact a physician.

Formulation Notes

Extended-Release Capsules

Metadata

Product Details

UPC / SKU3 49483-014-01
DSLD Entry Date2022-01-22
Product TypeVitamin
FormCapsule
DSLD ID264299
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
Compare

Similar Products

View all Niacin products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.