Sodium Polysulthionate and Folic Acid Capsules by Solubiomix — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
100% of ingredients have research evidence

A Label Compliance Grade

Product Label

Label for Sodium Polysulthionate and Folic Acid Capsules

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Label Data

1 Capsule(s) Serving Size

60 Servings

Single Vitamin and Mineral Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Folic Acid

1 mg

✅ 2.5× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 1mg UL 1.0mg

Sodium Polysulthionate

400 mg

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 400mg

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Usual dosage: Usual adult dose is 1-2 capsules twice daily or as prescribed by a medical practitioner.

⚠️ Warnings & Precautions

If you are pregnant or nursing, ask a healthcare professional.

Keep out of reach of children

Sodium polysulthionate and folic acid should be administered under the supervision of a licensed medical practitioner.

🧪 Formulation Notes

Made in the USA

Prescription (Rx) Folate

Proprietary matrix of alpha sulfur, sodium sulfate, sodium thiosulfate

Description: Sodium polysulthionate and folic acid is an orally administered prescription folate product for the dietary management of patients with unique nutritional needs requiring increased folate levels and management of suboptimal hydrogen sulfide metabolic imbalance.

Additional Information

Storage: Store at 20 degrees-25 degrees C (68 degrees-77 degrees F); excursions permitted to 15 degrees-30 degrees C (59 degrees-86 degrees F) [See USP Controlled Room Temperature.]

69499-904-60

Solubiomix Innovating Health Solutions

See attached labeling for complete product information

Product Details

UPC / SKU 3 69499-904-60 3

DSLD Entry Date 2021-12-18

Product Type Single Vitamin and Mineral

Form Capsule

Brand Solubiomix

DSLD ID 264223

Data Updated 2026-04-11

Research Evidence

363 Research Sources

57 Avg Quality Score

187 Meta Analysis

56 Systematic Review

54 Rct

29 Guideline

26 Clinical Trial

6 Cochrane Review

2 Regulatory Source

1 Other

1 Openfda Safety

A Homocysteine-lowering interventions for preventing cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies

Meta Analysis Digestive diseases and sciences 2021

PubMed DOI

A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis

Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021

PubMed DOI

A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis Nutrients 2024

PubMed DOI

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2022

PubMed DOI

A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants

Meta Analysis Critical reviews in food science and nutrition 2023

PubMed DOI

A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI

View all evidence for Folate →