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Glucosamine Chondroitin Plus MSM

product on market Other (e.g. tea bag) Spring Valley Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine hydrochloride and chondroitin sulfate are commonly used to support joint health and cartilage maintenance, with moderate evidence suggesting they may reduce joint discomfort. MSM is often included to further assist with inflammation and joint flexibility. Research on these ingredients generally shows a mixed but positive impact on joint function.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine Chondroitin Plus MSM
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Caplet(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
15 {Calories}
Total Carbohydrates
3 Gram(s) (1% DV)
Sodium
140 mg (6% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
1.2 Gram(s)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
MSM
1 Gram(s)
Market median: 1000.0mg (2 products)

Other Ingredients

Cellulose Crospovidone Contains <2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

SUGGESTED USE: For adults, take four (4) caplets daily, preferably with meals. As a reminder, discuss the supplements and medications you take with your health care providers.

Warnings & Precautions

CONTAINS SHELLFISH (SHRIMP, CRAB, LOBSTER, CRAYFISH) INGREDIENTS.

WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

KEEP OUT OF THE REACH OF CHILDREN.

FOR YOUR PROTECTION, DO NOT USE IF SAFETY SEAL UNDER CAP IT BROKEN OR MISSING.

Formulation Notes

CONTAINS SHELLFISH (SHRIMP, CRAB, LOBSTER, CRAYFISH) INGREDIENTS.

No Gluten, No Yeast, No Wheat, No Milk or Milk Derivatives, No Lactose, No Sugar, No Preservatives, No Soy, No Artificial Flavor.

Additional Information

VITAMIN #1 BRAND

JOINT HEALTH >>> Glucosamine Hydrochloride is a popular supplement that plays a role in the maintenance of joint cartilage. Chondroitin promotes healthy cartilage formation. MSM is an organic source of sulfur, a mineral that is vital in the formation of collagen, connective tissue, and healthy joint cartilage. MSM synergistically enhances the benefits of Glucosamine and Chondroitin.

QUALITY ASSURANCE GUARANTEE

- Produced under strict quality guidelines. - Verified by an independent, ISO 9001:2000 certified laboratory. UNCONDITIONALLY GUARANTEED BY REFUND OR REPLACEMENT

Item No. 44529 B30842W 04C

KEEP IN A DRY PLACE, TIGHTLY CLOSED AND AVOID EXCESSIVE HEAT.

Metadata

Product Details

UPC / SKU6 81131 69709 5
DSLD Entry Date2013-11-25
Product TypeNon-Nutrient/Non-Botanical
FormOther (e.g. tea bag)
DSLD ID26419
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.