Home/ Supplements/ Niacin/ Niacin (Vitamin B3) 500 mg

Niacin (Vitamin B3) 500 mg

product on market Capsule Solgar Safety: 60/100
60/100

Review before taking

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol levels and metabolic function, though research evidence for these effects varies. Due to a lower safety score, users should be aware of potential concerns such as skin flushing or liver enzyme changes. The overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Niacin is over 14 times the recommended upper limit for daily intake.

Label

Product Label

Label for Niacin (Vitamin B3) 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetable Capsule(s)
Serving Size
100
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Vegetable Cellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement for adults, take one (1) vegetable capsule daily, preferably with a meal or as directed by a healthcare practitioner. Do not take on an empty stomach. It is best to start nicotinic acid supplementation at a low strength, and gradually increase to meet your individual needs.

Warnings & Precautions

Notice: Consult your doctor before taking this product, or if you are switching niacin products. Nicotinic acid may cause a temporary skin flushing (hot feeling and skin redness), burning, itching, or rash. Sensitive individuals may experience unexpected drop of blood pressure or dizziness, especially if you have a history of low blood pressure or use antihypertensive medication. Do not take more than one capsule of this product per day, except under supervision of a physician.

Not intended for use by pregnant or nursing women.

Discontinue use and consult your healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

Do not use if outer bottle seal is missing or damaged.

Formulation Notes

Niacin / Vitamin B3, is a water-soluble vitamin and is part of the B complex. It is required for the metabolism of carbohydrates and protein into energy. Niacin also supports cardiovascular health, circulation and the health of the nervous system.

Solgar’s KOF-K certification #K-1250 K Parve (Kosher)

Cardiovascular support Supports energy metabolism

Non-GMO Gluten, wheat & dairy free GF Certified Gluten-free

Suitable for vegans

Free of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener and color.

Additional Information

For more information, call toll-free 1-877-SOLGAR 4 www.solgar.com

GF Certified Gluten-free K Parve (Kosher)

Store at room temperature.

Metadata

Product Details

UPC / SKU0 33984 01851 8
DSLD Entry Date2022-05-19
Product TypeVitamin
FormCapsule
BrandSolgar
DSLD ID263987
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
Compare

Similar Products

View all Niacin products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.