Daily Pure Pack Longevity by Pure Encapsulations — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
75% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

3 Capsule(s) Serving Size

28 Servings

Other Combinations Product Type

75% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin B12

2000 mcg (83333% DV)

📊 833.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 2.0mg

Mitopure Urolithin A

250 mg

Trans-Resveratrol

150 mg

📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)

This product: 150mg

Coenzyme Q-10

60 mg

📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)

This product: 60mg UL 1200mg

Other Ingredients

Glycerin Cellulose Water Plant Fiber

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 1 packet daily (3 capsules), with a meal.

⚠️ Warnings & Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

This product was sealed for your protection. Do not use if box or contents are opened or damaged.

🧪 Formulation Notes

Feel your best with core nutrients and antioxidants that promote healthy aging

Support your healthy aging where it matters most: at the cellular level.

Our Longevity pack offers important nourishment from Adenosyl/Hydroxy B12 and our exclusive healthy-aging formula: RENUAL.

Support healthy aging at the cellular level Increase cellular energy Power muscle function Support nerves and mitochondria

Each pack contains 2 RENUAL 1 Adenosyl/Hydroxy B12

Developed in collaboration with medical and nutritional experts using pure, premium ingredients FREE FROM unnecessary additives and many common allergens, and backed by verifiable science.

Additional Information

Directions: Fold this piece down. Thread first pack through the open slot. Take one packet daily.

As of 11/2/2020 in the healthcare practitioner channel.

This box is made from 30% post-consumer recycled fiber and can be recycled curbside. Discover the pure difference inside.

Facebook Twitter LinkedIn Instagram YouTube Tear here #1 Most Recommended brand by healthcare professional

Tear below to experience goodness encapsulated. It’s what’s on the inside that counts. Developed by nutritional & medical experts

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Product Details

UPC / SKU 7 66298 02389 2

DSLD Entry Date 2022-04-11

Product Type Other Combinations

Form Other (e.g. tea bag)

Brand Pure Encapsulations

DSLD ID 261870

Data Updated 2026-04-11

Research Evidence

237 Research Sources

53 Avg Quality Score

83 Meta Analysis

74 Systematic Review

45 Rct

29 Clinical Trial

2 Guideline

2 Regulatory Source

1 Openfda Safety

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency

Systematic Review The Cochrane database of systematic reviews 2018

PubMed DOI Cochrane

A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression

Meta Analysis Nutrients 2021

PubMed DOI

A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis

Systematic Review Irish journal of medical science 2024

PubMed DOI

B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis

Meta Analysis BMJ open gastroenterology 2020

PubMed DOI

B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes

Systematic Review The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels

Meta Analysis Nutrition reviews 2024

PubMed DOI

B Relationship between vitamin B12 levels and motor development: A systematic review

Systematic Review Clinical nutrition ESPEN 2024

PubMed DOI

B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis

Meta Analysis Frontiers in endocrinology 2023

PubMed DOI

View all evidence for Vitamin B12 →