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Osteo Bi-Flex Double Strength

product on market Other (e.g. tea bag) Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 12% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C and manganese are essential micronutrients that support connective tissue and bone health, though evidence for their efficacy in joint-specific supplements is limited. The profile contains basic nutrients and minerals with a high safety rating. Research on these specific ingredients for joint relief is generally moderate to limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex Double Strength
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Caplet(s)
Serving Size
36
Servings
Other Combinations
Product Type
12%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 {Calories}
Total Carbohydrates
3 Gram(s) (1% DV)
Vitamin C
60 mg (100% DV)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Sodium
45 mg (2% DV)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Joint Shield(TM) Proprietary Blend
1288 mg
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Crospovidone Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

3 PER DAY

NOTE: You have the option of taking three caplets together or spread throughout the day.

DIRECTIONS FOR ADULT USE: TAKE THREE (3) CAPLETS PER DAY PREFERABLY WITH FOOD.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

CAUTION: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

As a reminder, discuss the supplements and medications you take with your health care providers.

Formulation Notes

GLUCOSAMINE CHONDROITIN PLUS JOINT SHIELD(TM)

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Free of Gluten

Additional Information

NEW! SMOOTH WHITE COATING SAME FORMULA

#1 DOCTOR & PHARMACIST RECOMMENDED BRAND

Based on results of a GfK Healthcare 2011 survey among physicians who recommend a brand of Glucosamine and Chondroitin or Glucosamine supplements; and the results of a Pharmacy Times Survey among pharmacists who recommend a “bone/joint strengthener” dietary supplement, 2006-2012.

**52 week Nielsen ScanTrack data ending 8/25/12.

For information about arthritis, contact the Foundation at 1-800-568-4045 or www.arthritis.org

The natural aging process can add excessive stress on your joints. Annoying flare-ups can strike at any time.

Part No. 22-52526

HELPS REVITALIZE YOUR JOINTS* KEY BUILDING BLOCK OF CARTILAGE*

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

52526 00A B52514 LAB

40 POINTS

1-888-VITAHELP

Proud sponsor of the ARTHRITIS FOUNDATION(R)

Metadata

Product Details

UPC / SKU0 30768 03138 1
DSLD Entry Date2013-10-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID26051
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.