Liposomal B12 Folate TMG
87/100
This product is generally safe
- Folate: 1300mg is 1300.0× the Tolerable Upper Intake Level (1.0mg)
- 67% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 1300mg is 1300.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 mL
Serving Size
30
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Supplement Facts — Evidence Check
1300 mcg DFE
(325% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1300.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
3000 mcg
(125000% DV)
📊 1250.0× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
50 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Other Ingredients
Water, Purified
Sunflower Lecithin
Natural Flavors
Glycerin
Stevia leaf extract
Potassium Sorbate
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Directions: Take 1 milliliter (6 sprays) daily, or as directed by your healthcare practitioner. Shake before using. Use within 45 days of opening. This product is intended for oral use only.
⚠️ Warnings & Precautions
Pregnant or lactating women should consult their qualified healthcare provider prior to use.
🧪 Formulation Notes
Manufactured in the USA in a cGMP facility using the finest world ingredients.
As with all dietary supplements seek the advice of your healthcare provider prior to the use of this product.
Methyl-B12 + Methyl-Folate + Trimethylglycine (TMG) Optimal absorption methylation blend
Product Details
UPC / SKU
X002TCFV6V
DSLD Entry Date
2021-12-18
Product Type
Other Combinations
Form
Liquid
Brand
Core Med Science
DSLD ID
258415
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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