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Day

product on market Other (e.g. tea bag) Natrol Safety: 92/100
92/100

This product looks safe

  • Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

This profile combines B-vitamins with 5-HTP and L-Theanine, which are moderately supported by research for supporting mood and relaxation. While these ingredients are generally recognized as safe, the overall evidence coverage for this specific formulation is limited. The combination focuses on neurotransmitter precursors and amino acids to support cognitive function.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Day
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
10
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (590% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
333 mcg DFE (80% DV)
Exceeds UL by 333.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
50 mcg (2080% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
50 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
50 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)

Other Ingredients

Dibasic Calcium Phosphate Microcrystalline Cellulose Stearic Acid Hypromellose Silicon Dioxide Magnesium Stearate Cellulose Gum Methylcellulose Glycerin
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 white tablet, one or two times daily, with food. Do not exceed recommended dose.

Warnings & Precautions

Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition, or are taking prescription drugs, including drugs for depression, migraines, Parkinson's disease or psychiatric disorders. Do not use with other supplements containing L-Tryptophan or 5-HTP.

Do not use if you are pregnant, lactating or under the age of 18 years.

Tamper evident packaging. Tablets are sealed in blisters.

Formulation Notes

No: milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors or flavors, added sugar or preservatives

Natrol stress & anxiety daytime formula promotes calm and relaxation during the day: 5-HTP supports serotonin which helps enhance mood. Vitamins B-6, B-12 and Folic Acid help maintain emotional well-being. L-Theanine ensures relaxation without making you drowsy.

Promotes calm & relaxation Helps reduce occasional anxiety 100% drug-free

Vegetarian

Metadata

Product Details

UPC / SKU0 47469 05458 8
DSLD Entry Date2021-12-18
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandNatrol
DSLD ID257111
Data Updated2026-04-11
Research

Research Evidence

37
Research Sources
53
Avg Quality
22
Rct
10
Systematic Review
3
Meta Analysis
1
Clinical Trial
1
Openfda Safety
B Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials
Systematic Review Nutritional neuroscience 2026 PubMed DOI
B The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis
Meta Analysis Sleep medicine reviews 2025 PubMed DOI
B The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness
Rct Nutritional neuroscience 2010 PubMed DOI
B Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial
Rct Nutrients 2019 PubMed DOI
B The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025 PubMed DOI
B Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-Controlled Crossover Trial
Rct Nutrients 2022 PubMed DOI
B Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study
Rct Nutritional neuroscience 2025 PubMed DOI
B The combined effects of L-theanine and caffeine on cognitive performance and mood
Rct Nutritional neuroscience 2008 PubMed DOI
B Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2014 PubMed DOI
View all evidence for L Theanine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.