🟡 60/100

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  • Folate: 1666mg is 1666.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 1666mg is 1666.0× the Tolerable Upper Intake Level (1.0mg)

This product received a low safety score because the amount of folate it contains significantly exceeds the recommended maximum daily limit.

Label Data

1 Vegetarian Capsule(s) Serving Size
90 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1666 mcg DFE (417% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1666.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1666mg UL 1.0mg

Other Ingredients

Microcrystalline Cellulose Capsule Silica Rice Bran

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, adults take one (1) vegetarian capsule daily, or as directed by a health care professional.

⚠️ Warnings & Precautions

Caution: As with any supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing, or are under medical supervision for any reason.

Keep out of reach of children.

For serious adverse event reporting call (877) 455-2826.

🧪 Formulation Notes

We only put our name on formulas that meet our unrivaled quality standards, and we continue raising the bar on these standards without raising the bar on your budget. Our supplements are GMP (Good Manufacturing Practices) certified, ingredient verified, screened for heavy metals, and formulated without questionable fillers, artificial colors, sweeteners, flavors, and other problematic ingredients. We scrutinize every detail, so you don't have to, because we are, and always have been, your Original good4u Grocers. To your health, - The Isely Family

Our supplements are GMP (Good Manufacturing Practices) certified, ingredient verified, screened for heavy metals, and formulated without questionable fillers, artificial colors, sweeteners, flavors, and other problematic ingredients.

Metabolism support

Gluten free

Vegetarian

BPA Free

Contains no: Sugar, salt, dairy, yeast, wheat, gluten, corn, soy, preservatives, magnesium stearate, artificial colors or flavors.

Additional Information

Store in a cool, dry place and away from direct light.

GMP Good Manufacturing Practice

Made in USA

Product Details

UPC / SKU 8 49327 00365 9
DSLD Entry Date 2021-10-22
Product Type Vitamin
Form Capsule
DSLD ID 256885
Data Updated 2026-04-11

Research Evidence

363 Research Sources
57 Avg Quality Score
187 Meta Analysis
56 Systematic Review
54 Rct
29 Guideline
26 Clinical Trial
6 Cochrane Review
2 Regulatory Source
1 Other
1 Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025
View all evidence for Folate →

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