Centrum Immune & Digestive Support by Centrum — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
25% of ingredients have research evidence

B Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 Calorie(s)

Total Carbohydrates

1 Gram(s) (1% DV)

Vitamin A

1000 mcg (111% DV)

Vitamin C

80 mg (89% DV)

Vitamin E

9 mg (60% DV)

✅ Within RDA (0.6× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 9mg UL 1000mg

Zinc

11 mg (100% DV)

✅ Within RDA (1.0× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 11mg UL 40mg

Bacillus coagulans

20 mg

Organic Botanical Blend

400 mg

Other Ingredients

Microcrystalline Cellulose Hypromellose Contains less than 2% of

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: Adults: Take two (2) capsules daily with food. Do not exceed suggested use.

⚠️ Warnings & Precautions

Not formulated for use in children.

As with any supplement, if you are pregnant, nursing, or taking medication, consult your doctor before use.

Keep out of reach of children.

If taking other supplements, read label, since supplements may contain the same ingredient.

Do not use if inner foil seal under cap is torn or missing.

🧪 Formulation Notes

Proudly manufactured in a GMP facility.

Non-GMO and vegetarian.

Non-GMO and vegetarian. No synthetic colors, gelatin, dairy, soy, or nuts.

Immune support begins in your gut

Probiotics and vitamin C

Purposefully crafted to support your mind & body Our Bacillus Coagulans probiotic produces good bacteria to nourish the digestive tract where 70% of the immune system lives.

Vitamins A, C, & E, and Zinc help power your immune system daily. We've included an organic botanical blend of prebiotic blue agave inulin, astragalus root, and echinacea.

Additional Information

Store at room temperature, 15-30 degrees C (59-86 degrees F). Protect from heat, light and moisture.

New Look! gsk

Product Details

UPC / SKU 3 05731 28932 9

DSLD Entry Date 2021-07-27

Product Type Other Combinations

Form Capsule

Brand Centrum

DSLD ID 251338

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →