🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Extended Release Tablet(s) Serving Size
60 Servings
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 450mg

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Di-Calcium Phosphate Stearic Acid Magnesium Stearate Silica Pharmaceutical Glaze

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take one tablet twice daily, preferably in the morning and evening or as recommended by your health care practitioner.

⚠️ Warnings & Precautions

Note: If you are pregnant or nursing, consult your health care professional before using any herbal product.

Keep out of reach of children.

🧪 Formulation Notes

Nutritional Support for feelings of well-being.

Each Herbal Actives extended-release formula provides rapid and sustained results. Supplying the greatest concentration of active botanical principles, Herbal Actives St. John’s Wort maximizes the synergistic benefits of the whole flower, which naturally contains flavonoids, tannins, xanthones, monoterpenes and phytosterols. Guaranteed Maximum Activity: Each Herbal Actives formula is scientifically standardized to the highest level of active principles.

450 mg/0.3% - 0.5% Hypericin

Gluten Free

Free from artificial colors and preservatives. Free from all of the major allergens identified in the U.S. Food Allergen Labeling and Consumer Protection Act.

Additional Information

Maximum Guaranteed Activity

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 07350 0
DSLD Entry Date 2021-06-23
Product Type Botanical
Form Tablet or Pill
DSLD ID 249830
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
View all evidence for St Johns Wort →

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