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NiaPlex

product on market Capsule Karuna Safety: 80/100
80/100

This product is generally safe

  • Niacin: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin and chromium are utilized to support energy metabolism and blood glucose regulation. Research provides moderate evidence for these effects, though the overall evidence coverage for this specific formulation is limited. The ingredient profile maintains a favorable safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for NiaPlex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Single Vitamin and Mineral
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mg (5000% DV)
Exceeds UL by 28.6× (UL: 35 mg) 196 studies (A:5, B:63)
200 mcg (166% DV)
5.7× RDA — above typical dose 199 studies (A:1, B:55)

Other Ingredients

vegetarian capsules Rice Flour Vegetable Stearine
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: 2-4 capsules daily in divided doses, or as directed by your health care practitioner.

Warnings & Precautions

CAUTION: High doses of Niacin, in any form, should be used only under supervision.

Formulation Notes

Niacin/Inositol Complex

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

L004018E5/13

1209-LB4

Metadata

Product Details

UPC / SKU0 18647 01209 6
DSLD Entry Date2013-08-23
Product TypeSingle Vitamin and Mineral
FormCapsule
BrandKaruna
DSLD ID24766
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.