🟢 80/100

This product is generally safe

  • Niacin: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Niacin: 1000mg is 28.6× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
60 Servings
Single Vitamin and Mineral Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1000 mg (5000% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 28.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 1000mg UL 35mg
200 mcg (166% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg

Other Ingredients

vegetarian capsules Rice Flour Vegetable Stearine

Label Claims — Verification

All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use for adults: 2-4 capsules daily in divided doses, or as directed by your health care practitioner.

⚠️ Warnings & Precautions

CAUTION: High doses of Niacin, in any form, should be used only under supervision.

🧪 Formulation Notes

Niacin/Inositol Complex

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

L004018E5/13

1209-LB4

Product Details

UPC / SKU 0 18647 01209 6
DSLD Entry Date 2013-08-23
Product Type Single Vitamin and Mineral
Form Capsule
Brand Karuna
DSLD ID 24766
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

Compare Similar Products

View all Niacin products →