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MigraMaxx

product on market Capsule Karuna Safety: 87/100
87/100

This product is generally safe

  • Magnesium: 600mg is 1.7× the Tolerable Upper Intake Level (350mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

MigraMaxx contains Vitamin B2, Magnesium, and Butterbur, which are researched for their role in reducing migraine frequency and severity. There is moderate to strong evidence supporting the use of B2 and Magnesium for prophylaxis, while Butterbur shows efficacy but requires careful sourcing. The overall evidence coverage for this specific formulation remains limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 600mg is 1.7× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for MigraMaxx
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

200 mg (11765% DV)
153.8× RDA — above typical dose 13 studies (A:0, B:1)
600 mg (150% DV)
Exceeds UL by 1.7× (UL: 350 mg) 316 studies (A:8, B:159)
Butterbur
150 mg

Other Ingredients

vegetarian capsule Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: One capsule, with meals, three times daily, or as directed. Limit to one capsule per day for every 50 pounds of body weight.

Formulation Notes

Butterbur Extract (PA Free) with B2 and Magnesium

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place tightly capped.

Lot# 1104227

Butterbur extract (15% [petasin + isopetasin]). Purified to remove toxic (PA) pyrrolizidine alkaloids.

9139-LB1

Metadata

Product Details

DSLD Entry Date2013-08-23
Product TypeBotanical with Nutrients
FormCapsule
BrandKaruna
DSLD ID24669
Data Updated2026-04-10
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.